The High-fat Western Diet is more dangerous for the youngsters than for adults

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Researchers from several Bordeaux labs (France) studied how the Western Diet influenced the memory function of the mice weanlings versus adults and showed that although this diet similarly affected body composition and metabolism, only young mice suffered reduced memory flexibility (1).

The Western Diet term is used interchangeably with the High-fat diet. However, in fact, this diet is too high in carbohydrates to blame solely fat for its adverse effects (2, 3). The exact diet name is #D12451, Research Diets, New Brunswick and the ratio of combined carbohydrates and protein to fat content is way below the level where the fat can be effectively utilized in the process of lipolysis/ketogenesis: its the ketogenic ratio is 1:0.579 while the absolute anti-ketogenic ratio is 1:1 (read more about is here).

The high-fat diets that are low in carbohydrates, have absolutely opposite effects are are in fact metabo-protective and neuroprotective.

Sources

1. Juvenile, but Not Adult Exposure to High-Fat Diet Impairs Relational Memory and Hippocampal Neurogenesis in Mice
2. Carbohydrate-biased control of energy metabolism: the darker side of the selfish brain
   
3. Food Addiction and Obesity: Do Macronutrients Matter?