December 1, 2011 / Glucose, Ketogenic diet, Ketone bodies, Ketosis, ketogenesis, Methodology
It is interesting that while the ketogenic diet becomes well researched as a method for improving energy metabolism during quite a few medical conditions and the number of original research articles
Comments Off / Read More
November 30, 2011 / Alzheimer's, Glucose, Ketone bodies, Lactate
Chronic exposure to glucose due to the traditional Western diet impairs neuronal function and causes apoptosis (programmed neuronal death), concluded Drs Seneff & Wainwright (UK) and Mas
Comments Off / Read More
June 9, 2011 / Excitatory GABA, Ketone bodies, Lactate, Methodology, Pyruvate
Part 1. "Sweet slices are fine"? Part 2. Energy substrates: too sour? Part 3. Let the neurons breathe! Part 4. "Physiological" concentrations: what and where? What concentrations are physiolog
Comments Off / Read More
June 4, 2011 / Brain metabolism, Energy Substrates, Excitatory GABA, Glucose, Ketone bodies, Lactate, Pyruvate
Part 1. "Sweet slices are fine"? Part 2. Energy substrates: too sour? Part 3. Let the neurons breathe! Part 4. "Physiological" concentrations: what and where? [caption id="" align="alignleft"
Comments Off / Read More
May 7, 2011 / Applications, Energy Substrates, Glucose, Ketone bodies, Lactate, Pyruvate
Part 1. "Sweet slices are fine"? Part 2. Energy substrates: too sour? Part 3. Let the neurons breathe! Part 4. "Physiological" concentrations: what and where? Is glucose the absolutely exclus
November 27, 2010 / Energy Homeostasis, Energy Substrates, Glucose, Ketone bodies, Neuroprotectors
Medium-Chain Fatty Acids Improve Cognitive Function and Support In Vitro Synaptic Transmission During Acute Hypoglycemia (1) The brain can use alternative fuels such as monocarboxylic acids, lactat
November 16, 2010 / Excitatory GABA, Glucose, Ketone bodies, Methodology, Pyruvate
“They teach us in our institutes that GABA is excitatory in the neonates, should we still believe it?" (Excitatory GABA scandal?) There was an interesting development in the Department of Neur
November 15, 2010 / Epilepsy, Glucose, Ketone bodies, Lactate, Neuroprotectors, Pyruvate
A few interesting articles about glucose, lactate, and pyruvate and their neuroprotective functions. J Neurochem. 2010 Feb 15 Chronic in vitro ketosis is neuroprotective but not anticonvulsant. Ma
August 25, 2010 / Ketone bodies, Neuroprotectors
There are seven traits allowing ketones to serve as neuroprotectors during brain damage: they require only three steps to enter the Krebs cycle (footnote a) - compare with 9 steps obligatory f
June 15, 2010 / Astrocyte–neuron ketone shuttle, Ketone bodies
In the brain, to each one neurone, there are 9 astrocytes (1). They are surrounded by capillaries and are close to the both blood-brain and blood-cerebrospinal "the first cellular barrier encountered
March 17, 2010 / Ketone bodies, Methodology
D-beta-Hydroxybutyrate is a physiologically occurring D-isomer produced by hepatocytes and, to a lesser extent, by astrocytes. It is an alternative source of energy in the brain when glucose suppl
March 17, 2010 / Dementia, Excitatory GABA, Ketogenic diet, Ketone bodies, Neuroprotectors
Neuronal activity in immature neocortical neurons depends on the availability of ketone bodies in ACSF [caption id="" align="alignleft" width="120" caption="The provoking findings of Rheims et al. su
March 1, 2010 / Brain metabolism, Glucose, Ketone bodies
February 17, 2010 / Applications, Ketogenic diet, Ketone bodies
February 17, 2010 / Ketogenic diet, Ketone bodies, Theories
HYPOTHESES: Ketogenic diet reduces seizures by: a) promoting inhibitory action of GABA b) reducing cellular consequences of energy deficiency by supplying an alternative and 40 % more effici