April 17, 2010 / Energy Substrates, Excitatory GABA, Methodology, Neuroprotectors, Theories
As described in the post "On the mechanisms of brain protection by ketones", GABA, the principal brain chemical, normally acts to prevent hyperactivity in the neuronal networks. However, in the imma
March 17, 2010 / Ketone bodies, Methodology
D-beta-Hydroxybutyrate is a physiologically occurring D-isomer produced by hepatocytes and, to a lesser extent, by astrocytes. It is an alternative source of energy in the brain when glucose suppl
February 17, 2010 / Ethics in science, Ketosis, ketogenesis, Methodology
The large categories of disease for which ketones may have therapeutic effects are: (1) diseases of substrate insufficiency or insulin resistance, (2) diseases resulting from free radical damage
February 17, 2010 / Ketogenic diet, Ketone bodies, Ketosis, ketogenesis, Methodology
"Repeat after me three times, ketones are not evil, ketones are not evil, ketones are not evil... OK, now that we have gotten that out of the way..." -- Jeffrey Paul Krabb, MD In general medical
November 17, 2009 / Ketogenic diet, Ketone bodies, Methodology
The ketogenic diet's success rate greatly exceeds that of the medications. Its side effects, both cognitive and allergic, appear fewer than most available medications. Understand why changin