Archive for the Energy Homeostasis Category

November 27, 2010 / Energy Homeostasis, Energy Substrates, Glucose, Ketone bodies, Neuroprotectors

MCT and beta-hydroxybutirate protect cognitive and synaptic functions

Medium-Chain Fatty Acids Improve Cognitive Function and Support In Vitro Synaptic Transmission During Acute Hypoglycemia (1) The brain can use alternative fuels such as monocarboxylic acids, lactat

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July 19, 2010 / Energy Homeostasis, Energy Substrates, Excitatory GABA, Methodology

Neuronal activity in vitro and the in vivo reality

In the brain, neuronal electrical activity and intricate metabolic energy provisions are closely related. Although both functions have been painstakingly researched by electrophysiologists and biochem

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June 19, 2010 / Astrocyte–neuron ketone shuttle, Astrocyte–neuron lactate shuttle, Energy Homeostasis, Energy Substrates, Excitatory GABA, Methodology

Studies of GABA action: in vivo, in toto, and in vitro

On discrepancies of data from experiments on brain slices, in toto, and in vivo Let's start with the fundamental differences between environments depending on the types of experiments. (See Commenta

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March 17, 2010 / Energy Homeostasis, The selfish brain, Theories

The Selfish Brain Theory

The unique position of the brain as a body organ is characterized by: 1. its chemical isolation from the rest of the body by the blood-bran barrier 2. its high energy consumption: though weighing

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February 17, 2010 / Energy Homeostasis, Ketone bodies, Lactate, Pyruvate

Exceptional energy demands of the brain and energy substrates

In addition to glucose, other substrates must be considered along with fuel interactions, metabolic challenges, and cerebral maturation. (1) Ketone bodies are major metabolic fuels of the brain o

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