Archive for the Theories Category

November 22, 2010 / Energy Substrates, Excitatory GABA

Excitatory GABA: “Maybe It’s Not So Exciting After All!”

The Epilepsy Currents journal, Volume 10, Issue 5, pages 128–130, September/October 2010, published an article titled "Another Look at Early GABAergic Neurotransmission: Maybe It's Not So Excitin

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November 16, 2010 / Excitatory GABA, Glucose, Ketone bodies, Methodology, Pyruvate

Great Controversies in Neurobiogy

“They teach us in our institutes that GABA is excitatory in the neonates, should we still believe it?" (Excitatory GABA scandal?) There was an interesting development in the Department of Neur

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October 4, 2010 / Astrocyte–neuron lactate shuttle, Lactate, Neuroscience FAQ, Q&A

Lactate shuttle or glia-neuron metabolic cooperation

Original Q&A :: About these Q&A :: Other Q&A Q: Dr. Zilberter, I am a little bit confused in the area of what they call shuttles between neurons and glial cells. What the suttles do?

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September 20, 2010 / Excitatory GABA, Methodology, Neuroscience FAQ, Q&A

How does GABA behave in the intact brain?

Original Q&A :: About these Q&A :: Other Q&A Q: Dr. Zilberter, In your post at brainfuels.com, you cited several researchers and the closing phrase was: "The work undermined the role

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August 19, 2010 / Methodology, Theories

Books by Alexander Luria in English

A.R. Luria was one of the most significant psychological researchers and theorists of the 20th century. He is considered to have founded the field of neuropsychology, and he had a great influence on a

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July 31, 2010 / Astrocyte–neuron lactate shuttle, Lactate, Methodology

Comparison of lactate kinetics in vitro and in vivo is to be done

Glucose is an energy source for both neurons and glia in the adult brain but lactate, one of the monocarboxylic acids, being converted from pyruvate in astrocytes and supplied to neuron ("astrocyte-ne

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July 19, 2010 / Energy Homeostasis, Energy Substrates, Excitatory GABA, Methodology

Neuronal activity in vitro and the in vivo reality

In the brain, neuronal electrical activity and intricate metabolic energy provisions are closely related. Although both functions have been painstakingly researched by electrophysiologists and biochem

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July 1, 2010 / Theories

An acupuncture theory based on Rexed laminae organization compared with neurocomputers

The best (imho) of the few known conventional theories of acupuncture belongs to an interdisciplinary team of theoretical biologists and brain morphologists working under Dr. Dmitri Chernavski, an aca

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June 19, 2010 / Astrocyte–neuron ketone shuttle, Astrocyte–neuron lactate shuttle, Energy Homeostasis, Energy Substrates, Excitatory GABA, Methodology

Studies of GABA action: in vivo, in toto, and in vitro

On discrepancies of data from experiments on brain slices, in toto, and in vivo Let's start with the fundamental differences between environments depending on the types of experiments. (See Commenta

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June 15, 2010 / Astrocyte–neuron ketone shuttle, Ketone bodies

The astrocyte–neuron ketone body shuttle

In the brain, to each one neurone, there are 9 astrocytes (1). They are surrounded by capillaries and are close to the both blood-brain and blood-cerebrospinal "the first cellular barrier encountered

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June 13, 2010 / Astrocyte–neuron lactate shuttle, Glucose, Lactate

Glucose or lactate as fuels in mature brain: whose primacy?

Updates: Glucose versus lactate in immature brain slices Brain metabolism updates: Sweet and sour recipes for the brain Astrocyte-neuron lactate transport is required for long-term memory formation

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May 17, 2010 / Adaptive regulation, Glucose

The brain believes the sweet taste rather than metabolic facts

It's a well known fact that drinking carbohydrate-rich beverages during high-intensity exercise improves performance even if it's relatively short, which made researchers suspect that direct metabolic

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May 7, 2010 / Adaptive regulation, Applications, Hormesis

Prescription-strength stress as a medicine

Reflexo-therapy research results and possible approaches to its mechanisms Related: A theory of acupuncture, spinal cord, and endorphins There is only a couple direct research on the reflexo-ther

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May 6, 2010 / Intrinsic brain activity, Theories

The resting brain is not silent

Is the brain just a vessel, which is empty until the outside world fills it with reflections of its elements? What's going on inside the calm brain of a quiet person? The current view is that it fluct

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April 17, 2010 / Energy Substrates, Excitatory GABA, Methodology, Neuroprotectors, Theories

On the theory of excitatory GABA

As described in the post "On the mechanisms of brain protection by ketones", GABA, the principal brain chemical, normally  acts to prevent hyperactivity in the neuronal networks. However, in the imma

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