Posts Tagged Energy Substrates

June 4, 2011 / Brain metabolism, Energy Substrates, Excitatory GABA, Glucose, Ketone bodies, Lactate, Pyruvate

“Brain metabolism in vitro” and those sour energy substrates

Part 1. "Sweet slices are fine"? Part 2. Energy substrates: too sour? Part 3. Let the neurons breathe! Part 4. "Physiological" concentrations: what and where? [caption id="" align="alignleft"

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May 23, 2011 / Astrocyte–neuron lactate shuttle, Lactate

The metabolic rate of plasma-borne lactate is a function of brain lactate concentration

In the Journal club section of the Journal of Neuroscience (written exclusively by graduate students or postdoctoral fellows), a review by C. Figley from Johns Hopkins University and Kennedy Krieger I

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July 19, 2010 / Energy Homeostasis, Energy Substrates, Excitatory GABA, Methodology

Neuronal activity in vitro and the in vivo reality

In the brain, neuronal electrical activity and intricate metabolic energy provisions are closely related. Although both functions have been painstakingly researched by electrophysiologists and biochem

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March 17, 2010 / Neuroprotectors, Pyruvate

Pyruvate protects neurons against A-beta peptides characteristic for Alzheimer’s

Pyruvate is one of major energy carriers in the brain, it is shown to be protective against damaging consequences of neurotoxins, such as hydrogen peroxide, glutamate, zinc, and copper/cysteine (1). P

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March 1, 2010 / Brain metabolism, Glucose, Ketone bodies