The MMM of aging: mood, memory, movement

“Thinking, Moving, Feeling”: What Do They Have in Common?

This question opens a review of age-related declines, their inter-relationships, mechanisms, and the ways to postpone if not avoid them. The authors discuss the occurrence of depression and mood disorders during normal, premature or pathological aging, reminding that the usual suspects – serotonin and norepinephrine – indeed decline as people age as well as in Alzheimer’s and Parkinson’s diseases (A, Granholm et al., Mood, Memory and Movement: An Age-Related Neurodegenerative Complex? Curr Aging Sci. 2008 July ; 1(2): 133–139.)

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Is ketosis natural?

“Repeat after me three times, ketones are not evil, ketones are not evil, ketones are not evil… OK, now that we have gotten that out of the way…”

– Jeffrey Paul Krabb, MD

In general medical literature, ketosis is often defined as abnormally high levels of ketone bodies in the blood.

Meanwhile, ketosis — but not ketoacidosis! — naturally occurs:

  • Every morning after the night fast
  • During fasting and calorie restriction
  • After intensive prolonged exercise
  • As a result of a diet significantly higher in fat comparing tha in carbohydrates
  • Early in ontogenesis

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